Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: safety and parasite growth dynamics

<p>In endemic settings it is known that natural malaria immunity is gradually acquired following repeated exposures. Here we sought to assess whether similar acquisition of blood-stage malaria immunity would occur following repeated parasite exposure by controlled human malaria infection (CHMI...

Full description

Bibliographic Details
Main Authors: Salkeld, J, Themistocleous, Y, Barrett, JR, Mitton, CH, Rawlinson, TA, Payne, RO, Hou, MM, Khozoee, B, Edwards, NJ, Nielsen, CM, Sandoval, DM, Bach, FA, Nahrendorf, W, Ramon, RL, Baker, M, Ramos-Lopez, F, Folegatti, PM, Quinkert, D, Ellis, KJ, Poulton, ID, Lawrie, AM, Cho, J-S, Nugent, FL, Spence, PJ, Silk, SE, Draper, SJ, Minassian, AM
Format: Journal article
Language:English
Published: Frontiers Media 2022