DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma.

DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma.

PURPOSE: DNA replication licensing factors and Aurora kinases play critical roles in maintaining genomic integrity. We used multiparameter analyses of these cell cycle regulatory proteins to investigate their role in the progression of epithelial ovarian carcinoma (EOC). EXPERIMENTAL DESIGN: In a c...

書誌詳細
主要な著者:	Kulkarni, A, Loddo, M, Leo, E, Rashid, M, Eward, K, Fanshawe, T, Butcher, J, Frost, A, Ledermann, J, Williams, G, Stoeber, K
フォーマット:	Journal article
言語:	English
出版事項:	2007

類似資料

DNA replication licensing in somatic and germ cells.
著者:: Eward, K, 等
出版事項: (2004)

DNA replication licensing in somatic and germ cells
著者:: Eward, K, 等
出版事項: (2004)

DNA replication licensing and cell cycle kinetics of normal and neoplastic breast.
著者:: Shetty, A, 等
出版事項: (2005)

Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells.
著者:: Kingsbury, SR, 等
出版事項: (2005)

Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer.
著者:: Dudderidge, T, 等
出版事項: (2007)

Aurora kinases in ovarian cancer
著者:: Valentina Gambardella, 等
出版事項: (2020-10-01)

Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells
著者:: Ding YH, 等
出版事項: (2015-01-01)

EWSR1 prevents the induction of aneuploidy through direct regulation of Aurora B
著者:: Haeyoung Kim, 等
出版事項: (2023-02-01)

Specific distribution of overexpressed aurora B kinase in interphase normal epithelial cells
著者:: Foong Charlene, 等
出版事項: (2005-11-01)

Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
著者:: McDonald John F, 等
出版事項: (2008-12-01)

Targeting Aurora A Kinase (AAK) in Platinum-Resistant High Grade Serous Ovarian Cancer
著者:: Ram N. Ganapathi, 等
出版事項: (2020-08-01)

Mcm2, Geminin, and KI67 define proliferative state and are prognostic markers in renal cell carcinoma.
著者:: Dudderidge, T, 等
出版事項: (2005)

Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
著者:: Helfrid Hochegger, 等
出版事項: (2013-01-01)

Aurora B and Aurora C pools at two chromosomal regions collaboratively maintain chromosome alignment and prevent aneuploidy at the second meiotic division in mammalian oocytes
著者:: Anna Kouznetsova, 等
出版事項: (2024-09-01)

Aurora kinase protein family in Trypanosoma cruzi: Novel role of an AUK-B homologue in kinetoplast replication.
著者:: Matías Fassolari, 等
出版事項: (2019-03-01)

Ubiquitin-mediated degradation of Aurora kinases
著者:: Catherine eLindon, 等
出版事項: (2016-01-01)

Re-replication of a centromere induces chromosomal instability and aneuploidy.
著者:: Stacey L Hanlon, 等
出版事項: (2015-04-01)

Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex
著者:: Pinar Altiner, 等
出版事項: (2023-10-01)

The non-canonical role of Aurora-A in DNA replication
著者:: Takaaki eTsunematsu, 等
出版事項: (2015-08-01)

Functions of Aurora kinase C in meiosis and cancer
著者:: Suzanne M. Quartuccio, 等
出版事項: (2015-08-01)

Aurora kinases orchestrate mitosis; who are the players?
著者:: Molla Annie
出版事項: (2010-08-01)

Aurora kinase inhibitors: current status and outlook
著者:: Vassilios eBavetsias, 等
出版事項: (2015-12-01)

Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes.
著者:: Ahmed Z Balboula, 等
出版事項: (2014-02-01)

Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis
著者:: Rajesh K Kasam, 等
出版事項: (2020-08-01)

Aurora kinase as a putative target to tick control
著者:: Bruno Moraes, 等
出版事項: (2024-08-01)

Aurora kinases as targets in drug-resistant neuroblastoma cells.
著者:: Martin Michaelis, 等
出版事項: (2014-01-01)

Aurora Kinase A Regulation by Cysteine Oxidative Modification
著者:: In-Gyun Lee, 等
出版事項: (2023-02-01)

Aurora kinases: Generators of spatial control during mitosis
著者:: Aamir Ali, 等
出版事項: (2023-03-01)

Aurora kinase A is essential for meiosis in mouse oocytes.
著者:: Cecilia S Blengini, 等
出版事項: (2021-04-01)

The functional diversity of Aurora kinases: a comprehensive review
著者:: Estelle Willems, 等
出版事項: (2018-09-01)

Evolutionary reconstruction and population genetics analysis of aurora kinases.
著者:: Balu Kamaraj, 等
出版事項: (2013-01-01)

Novel markers of cell kinetics to evaluate progression from cirrhosis to hepatocellular carcinoma.
著者:: Quaglia, A, 等
出版事項: (2006)

A Cell Biologist’s Field Guide to Aurora Kinase Inhibitors
著者:: Christian eDe Groot, 等
出版事項: (2015-12-01)

DNA replication origins retain mobile licensing proteins
著者:: Humberto Sánchez, 等
出版事項: (2021-03-01)

Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial–mesenchymal transition in triple-negative breast cancer
著者:: Xi Chen, 等
出版事項: (2024-12-01)

Aurora A Kinase Regulates Mammary Epithelial Cell Fate by Determining Mitotic Spindle Orientation in a Notch-Dependent Manner
著者:: Joseph L. Regan, 等
出版事項: (2013-07-01)

Inhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cells.
著者:: Anna L Illert, 等
出版事項: (2014-01-01)

Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer
著者:: Ganjei-Azar Parvin, 等
出版事項: (2011-03-01)

Aurora-A kinase is differentially expressed in the nucleus and cytoplasm in normal Müllerian epithelium and benign, borderline and malignant serous ovarian neoplasms
著者:: Khaled J. Alkhateeb, 等
出版事項: (2021-10-01)

Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors
著者:: Mrunal Jadhav, 等
出版事項: (2021-08-01)