Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo

Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected. Current drug treatment options are limited and lack efficacy against the worm, preventing an eradication programme. It is theref...

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Hlavní autoři: Partridge, F, Murphy, E, Willis, N, Bataille, C, Forman, R, Heyer-Chauhan, N, Marinič, B, Sowood, D, Wynne, G, Else, K, Russell, A, Sattelle, D
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2017