Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo
Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected. Current drug treatment options are limited and lack efficacy against the worm, preventing an eradication programme. It is theref...
Hlavní autoři: | Partridge, F, Murphy, E, Willis, N, Bataille, C, Forman, R, Heyer-Chauhan, N, Marinič, B, Sowood, D, Wynne, G, Else, K, Russell, A, Sattelle, D |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Public Library of Science
2017
|
Podobné jednotky
-
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm
Autor: Partridge, F, a další
Vydáno: (2018) -
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.
Autor: Frederick A Partridge, a další
Vydáno: (2018-07-01) -
Anthelmintic drug discovery: target identification, screening methods and the role of open science
Autor: Frederick A. Partridge, a další
Vydáno: (2020-06-01) -
The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms.
Autor: Tina V A Hansen, a další
Vydáno: (2021-02-01) -
A drug repurposing screen for whipworms informed by comparative genomics.
Autor: Avril Coghlan, a další
Vydáno: (2023-09-01)