Structural studies of the human GABAB receptor using cryo-electron microscopy

<p>The metabotropic gamma-aminobutyric acid type-B receptor (GABABR) mediates slow and prolonged inhibitory neurotransmission in the mammalian nervous system. GABABR belongs to the Class C GPCR family and is the first GPCR reported to function as an obligate heterodimer. Structurally, GABABR d...

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Bibliographic Details
Main Author: Sun, Z
Other Authors: Aricescu, R
Format: Thesis
Language:English
Published: 2018