Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis

Intestinal immune responses to microbes are controlled by the cytokine IL-10 to avoid immune pathology. Here, we use single-cell RNA sequencing of colon lamina propria leukocytes (LPLs) along with RNA-seq and ATAC-seq of purified CD4<sup>+</sup> T cells to show that the transcription fac...

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Bibliographic Details
Main Authors:	Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A
Format:	Journal article
Language:	English
Published:	Springer Nature 2024

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis

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