Real-Time Monitoring of the Dephosphorylating Activity of Protein Tyrosine Phosphatases Using Microarrays with 3-Nitrophosphotyrosine Substrates

Phosphatases and kinases regulate the crucial phosphorylation post-translational modification. In spite of their similarly important role in many diseases and therapeutic potential, phosphatases have received arguably less attention. One reason for this is a scarcity of high-throughput phosphatase a...

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Bibliographic Details
Main Authors: van Ameijde, J, Overvoorde, J, Knapp, S, den Hertog, J, Ruijtenbeek, R, Liskamp, R
Format: Journal article
Language:English
Published: 2013