Real-Time Monitoring of the Dephosphorylating Activity of Protein Tyrosine Phosphatases Using Microarrays with 3-Nitrophosphotyrosine Substrates
Phosphatases and kinases regulate the crucial phosphorylation post-translational modification. In spite of their similarly important role in many diseases and therapeutic potential, phosphatases have received arguably less attention. One reason for this is a scarcity of high-throughput phosphatase a...
Main Authors: | van Ameijde, J, Overvoorde, J, Knapp, S, den Hertog, J, Ruijtenbeek, R, Liskamp, R |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2013
|
Similar Items
-
A versatile spectrophotometric protein tyrosine phosphatase assay based on 3-nitrophosphotyrosine containing substrates.
by: van Ameijde, J, et al.
Published: (2014) -
A new way to interrogate PTPs
by: Van Ameijde, J, et al.
Published: (2014) -
Protocol to assess substrate dephosphorylation by serine/threonine phosphoprotein phosphatases in vitro
by: Jason S. Wasserman, et al.
Published: (2023-06-01) -
Tyrosine phosphatase SHP2 aggravates tumor progression and glycolysis by dephosphorylating PKM2 in gastric cancer
by: Peiyun Wang, et al.
Published: (2024-04-01) -
"Licensed to kill": tyrosine dephosphorylation and Bak activation.
by: Fox, J, et al.
Published: (2011)