Quantification of the anti-influenza drug zanamivir in plasma using high-throughput HILIC-MS/MS.

BACKGROUND: parenteral zanamivir is a promising drug for the treatment of severe influenza. However, quantification of this polar drug in biological matrices has traditionally been difficult and the methods developed have been relatively insensitive. RESULTS: a high-throughput bioanalytical method f...

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Bibliographic Details
Main Authors: Lindegardh, N, Hanpithakpong, W, Kamanikom, B, Farrar, J, Hien, T, Singhasivanon, P, White, N, Day, N
Format: Journal article
Language:English
Published: 2011