Alpha-synuclein dysfunction in Lewy body diseases.

alpha-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind to lipid membranes and acquire a partial alpha-helical conformation. Its relevance to Parkinson's disease (PD) is based on mutations found in familial cases of the disease and its presence in filame...

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Bibliographic Details
Main Authors: Tofaris, G, Spillantini, MG
Format: Journal article
Language:English
Published: 2005