Alpha-synuclein dysfunction in Lewy body diseases.
alpha-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind to lipid membranes and acquire a partial alpha-helical conformation. Its relevance to Parkinson's disease (PD) is based on mutations found in familial cases of the disease and its presence in filame...
Main Authors: | Tofaris, G, Spillantini, MG |
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Format: | Journal article |
Language: | English |
Published: |
2005
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