The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
<p>Telomerase is expressed in the majority (>85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...
Prif Awdur: | Jackson, M |
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Awduron Eraill: | Vallis, K |
Fformat: | Traethawd Ymchwil |
Iaith: | English |
Cyhoeddwyd: |
2013
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Pynciau: |
Eitemau Tebyg
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Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
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Radiopharmaceutical Validation for Clinical Use
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