The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
<p>Telomerase is expressed in the majority (>85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...
Autore principale: | Jackson, M |
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Altri autori: | Vallis, K |
Natura: | Tesi |
Lingua: | English |
Pubblicazione: |
2013
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Soggetti: |
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