pKID binds to KIX via an unstructured transition state with nonnative interactions

Understanding the detailed mechanism of interaction of intrinsically disordered proteins with their partners is crucial to comprehend their functions in signaling and transcription. Through its interaction with KIX, the disordered pKID region of CREB protein is central in the transcription of cAMP r...

Full description

Bibliographic Details
Main Authors: Dahal, L, Kwan, TOC, Shammas, SL, Clarke, J
Format: Journal article
Language:English
Published: Elsevier 2017