Validating predictive sequence analysis in polyketide stereochemical determination though the synthesis of stambomycin D
<p>In recent years, predictive gene sequence analysis of biosynthetic enzymes has emerged as a powerful tool for the stereochemical determination of natural products. The stambomycins, a family of 51-membered bioactive macrolides isolated from <em>Streptomyces ambofaciens</em>, ar...
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Format: | Thesis |
Language: | English |
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2023
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