Functional characterisation of the osteoarthritis genetic risk residing at ALDH1A2 identifies rs12915901 as a key target variant
To identify the functional single nucleotide polymorphisms (SNPs) and mechanisms conferring increased hand osteoarthritis (OA) risk at the ALDH1A2 locus, which is a retinoic acid (RA) regulatory gene.Tissues from 247 knee, hip or hand OA patients who had undergone joint surgery were included. RNA-se...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2018
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