Pathogenic mechanisms in murine autoimmune thyroiditis: short- and long-term effects of in vivo depletion of CD4+ and CD8+ cells.

Pathogenic mechanisms in murine autoimmune thyroiditis: short- and long-term effects of in vivo depletion of CD4+ and CD8+ cells.

Both murine CD4+ and CD8+ cells are found in the thyroid infiltrate in experimental autoimmune thyroiditis (EAT) induced with mouse thyroglobulin (MTg). MTg activation of immune cells in vitro enables CD4+ cells to transfer thyroiditis adoptively and to aid the cytotoxic capacity of CD8+ cells for t...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Kong, Y, Waldmann, H, Cobbold, S, Giraldo, A, Fuller, B, Simon, L
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1989

Eitemau Tebyg

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