Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2.

PepT1 and PepT2 are major facilitator superfamily (MFS) transporters that utilize a proton gradient to drive the uptake of di- and tri-peptides in the small intestine and kidney, respectively. They are the major routes by which we absorb dietary nitrogen and many orally administered drugs. Here, we...

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Bibliographic Details
Main Authors: Newstead, S, Drew, D, Cameron, A, Postis, V, Xia, X, Fowler, P, Ingram, J, Carpenter, E, Sansom, MS, McPherson, M, Baldwin, SA, Iwata, S
Format: Journal article
Language:English
Published: 2011