Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2.

PepT1 and PepT2 are major facilitator superfamily (MFS) transporters that utilize a proton gradient to drive the uptake of di- and tri-peptides in the small intestine and kidney, respectively. They are the major routes by which we absorb dietary nitrogen and many orally administered drugs. Here, we...

Descrición completa

Detalles Bibliográficos
Main Authors: Newstead, S, Drew, D, Cameron, A, Postis, V, Xia, X, Fowler, P, Ingram, J, Carpenter, E, Sansom, MS, McPherson, M, Baldwin, SA, Iwata, S
Formato: Journal article
Idioma:English
Publicado: 2011