The role of clearance mechanisms in the kinetics of toxic protein aggregates involved in neurodegenerative diseases

The deposition of pathological protein aggregates in the brain plays a central role in cognitive decline and structural damage associated with neurodegenerative diseases. In Alzheimer’s disease, the formation of Amyloid-beta plaques and neurofibrillary tangles of the tau protein is associated with t...

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Bibliographic Details
Main Authors: Thompson, T, Meisl, G, Knowles, TPJ
Format: Journal article
Language:English
Published: AIP Publishing 2021