Polypyrimidine tract-binding protein stimulates the poliovirus IRES by modulating eIF4G binding.

Tethered hydroxyl-radical probing has been used to determine the orientation of binding of polypyrimidine tract-binding protein (PTB) to the poliovirus type 1 (Mahoney) (PV-1(M)) internal ribosome entry site/segment (IRES)-the question of which RNA-binding domain (RBD) binds to which sites on the IR...

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Bibliographic Details
Main Authors: Kafasla, P, Morgner, N, Robinson, C, Jackson, R
Format: Journal article
Language:English
Published: 2010