Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system.
The African trypanosome, Trypanosoma brucei possesses a large and unique intraflagellar structure called the paraflagellar rod (PFR). The PFR is composed of 2 major proteins, PFRA and PFRC. We have generated an inducible mutant trypanosome cell line (snl-2) that expresses linked inverted copies of a...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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