Transcription by an immobilized RNA polymerase from bacteriophage T7 and the topology of transcription.

It is often assumed that a polymerase moves along the template as it synthesizes RNA. However, a polymerase that tracks along a helical strand will generate a transcript that is entwined about the template. No such interlocking results if the polymerase is immobile and the template moves past it. Th...

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Detalles Bibliográficos
Main Authors: Cook, P, Gove, F
Formato: Journal article
Idioma:English
Publicado: 1992

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