Serum HCoV-spike specific antibodies do not protect against subsequent SARS-CoV-2 infection in children and adolescents

SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalization. Why this is so remains unclear. Here we explore the potential for protection due to pre-existing cross-reactive seasonal coronavirus antibodies and compare the rate of anti...

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Bibliographic Details
Main Authors: Ratcliffe, H, Tiley, K, Longet, S, Tonry, C, Roarty, C, Watson, C, Amirthalingam, G, Vichos, I, Morey, E, Douglas, NL, Marinou, S, Plested, E, Aley, PK, Galiza, E, Faust, SN, Hughes, S, Murray, C, Roderick, MR, Shackley, F, Oddie, S, Lee, TWR, Turner, DPJ, Raman, M, Owens, S, Turner, PJ, Cockerill, H, Lopez Bernal, J, Ijaz, S, Poh, J, Shute, J, Linley, E, Borrow, R, Hoschler, K, Brown, KE, Carroll, MW, Klenerman, P, Dunachie, SJ, Ramsay, M, Voysey, M, Waterfield, T, Snape, MD
Format: Journal article
Language:English
Published: Elsevier 2023