Unusual antigen presentation offers new insight into HIV vaccine design

Recent findings with a rhesus monkey cytomegalovirus based simian immunodeficiency virus vaccine have identified strong CD8+ T cell responses that are restricted by MHC-E. Also mycobacteria specific CD8+ T cells, that are MHC-E restricted, have been identified. MHC-E therefore can present a wide ran...

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Bibliographic Details
Main Authors: McMichael, A, Picker, L
Format: Journal article
Language:English
Published: Elsevier 2017