Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine.

We have examined the kinetics of triple helix formation of oligonucleotides that contain the nucleotide analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine (bis-amino-U, BAU), which forms very stable base triplets with AT. Triplex stability is determined by both the number and location o...

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Bibliographic Details
Main Authors: Rusling, D, Broughton-Head, V, Tuck, A, Khairallah, H, Osborne, S, Brown, T, Fox, K
Format: Journal article
Language:English
Published: 2008