Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.

BACKGROUND: CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C. In contrast, in evolving chronic hepatitis C CD4+ T cell helper responses appear to be absent or short-lived, using functional assays. METH...

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Bibliographic Details
Main Authors:	Lucas, M, Ulsenheimer, A, Pfafferot, K, Heeg, M, Gaudieri, S, Gruner, N, Rauch, A, Gerlach, J, Jung, M, Zachoval, R, Pape, G, Schraut, W, Santantonio, T, Nitschko, H, Obermeier, M, Phillips, R, Scriba, T, Semmo, N, Day, C, Weber, J, Fidler, S, Thimme, R, Haberstroh, A, Baumert, T, Klenerman, P, Diepolder, H
Format:	Journal article
Language:	English
Published:	Public Library of Science 2007

Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.

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