Severe cytopenias associated with the sequential use of busulphan and interferon-alpha in chronic myeloid leukaemia.
We describe four patients who developed severe thrombocytopenia which progressed to aplasia after the use of alpha-interferon in maintenance therapy of chronic phase CML after busulphan induction. On reviewing over 400 patients in the MRC CML III trial we found that there is a risk of cytopenia deve...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1994
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