Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate-amodiaquine fixed dose combination or artemether-lumefantrine in Liberia

Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug re...

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Bibliographic Details
Main Authors: Otienoburu, SD, Maïga-Ascofaré, O, Schramm, B, Jullien, V, Jones, JJ, Zolia, YM, Houzé, P, Ashley, EA, Kiechel, JR, Guérin, PJ, Le Bras, J, Houzé, S
Format: Journal article
Language:English
Published: BioMed Central 2016