In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis.

<h4>OBJECTIVE:</h4> <p>To develop enzyme-activatable Förster resonance energy transfer (FRET) substrate probes to detect matrix metalloproteinase 12 (MMP-12) and MMP-13 activities in vivo in mouse models of inflammatory arthritis.</p> <h4>METHODS:</h4> <p>Pe...

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Bibliographic Details
Main Authors: Lim, N, Meinjohanns, E, Bou-Gharios, G, Gompels, L, Nuti, E, Rossello, A, Devel, L, Dive, V, Meldal, M, Nagase, H
Format: Journal article
Language:English
Published: Wiley 2014