Cross-reactivity and anti-viral function of dengue capsid and NS3-specific memory t cells toward Zika virus

Zika virus (ZIKV), a flavivirus with homology to dengue virus (DENV), is spreading to areas of DENV hyper-endemicity. Heterologous T cell immunity, whereby virus-specific memory T cells are activated by variant peptides derived from a different virus, can lead to enhanced viral clearance or diminish...

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Bibliographic Details
Main Authors: Lim, M, Kumaran, E, Tan, H, Lye, D, Leo, Y, Ooi, E, Macary, P, Bertoletti, A, Rivino, L
Format: Journal article
Language:English
Published: Frontiers Media 2018