DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility

<strong>Aim of the study</strong> A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as ‘epigenetic clock’, has been linked with cancer risk factors. This study aimed to e...

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Main Authors: Ambatipudi, S, Horvath, S, Perrier, F, Cuenin, C, Hernandez-Vargas, H, Le Calvez-Kelm, F, Durand, G, Byrnes, G, Ferrari, P, Bouaoun, L, Sklias, A, Chajes, V, Overvad, K, Severi, G, Baglietto, L, Clavel-Chapelon, F, Kaaks, R, Barrdahl, M, Boeing, H, Trichopoulou, A, Lagiou, P, Naska, A, Masala, G, Agnoli, C, Polidoro, S, Tumino, R, Panico, S, Dollé, M, Peeters, PHM, Onland-Moret, NC, Sandanger, TM, Nøst, TH, Weiderpass, E, Quirós, JR, Agudo, A, Rodriguez-Barranco, M, Castaño, JM, Barricarte, A, Fernández, AM, Travis, RC, Vineis, P, Muller, DC, Riboli, E, Gunter, M, Romieu, I, Herceg, Z
Format: Journal article
Language:English
Published: Elsevier 2017