A mechanism of release of calreticulin from cells during apoptosis.

Calreticulin (CRT) is an endoplasmic reticulum (ER) chaperone responsible for glycoprotein folding and Ca(2+) homeostasis. CRT also has extracellular functions, e.g. tumor and apoptotic cell recognition and wound healing, but the mechanism of CRT extracellular release is unknown. Cytosolic localizat...

Полное описание

Библиографические подробности
Главные авторы: Tarr, J, Young, P, Morse, R, Shaw, D, Haigh, R, Petrov, P, Johnson, S, Winyard, P, Eggleton, P
Формат: Journal article
Язык:English
Опубликовано: 2010