Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

BACKGROUND: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph node metastasis and poor survival. The goal of...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Stevens, K, Garcia-Closas, M, Fredericksen, Z, Kosel, M, Pankratz, V, Hopper, J, Dite, G, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Tollenaar, R, Fasching, P, Beckmann, M, Hein, A, Ekici, AB, Johnson, N, Peto, J, dos Santos Silva, I, Gibson, L, Sawyer, E, Tomlinson, I, Kerin, M, Chanock, S
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2011

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