Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

BACKGROUND: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph node metastasis and poor survival. The goal of...

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Main Authors:	Stevens, K, Garcia-Closas, M, Fredericksen, Z, Kosel, M, Pankratz, V, Hopper, J, Dite, G, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Tollenaar, R, Fasching, P, Beckmann, M, Hein, A, Ekici, AB, Johnson, N, Peto, J, dos Santos Silva, I, Gibson, L, Sawyer, E, Tomlinson, I, Kerin, M, Chanock, S
פורמט:	Journal article
שפה:	English
יצא לאור:	2011

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

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