Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.

Asthma is caused by a combination of poorly understood genetic and environmental factors. We have systematically mapped the effects of single nucleotide polymorphisms (SNPs) on the presence of childhood onset asthma by genome-wide association. We characterized more than 317,000 SNPs in DNA from 994...

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Hlavní autoři: Moffatt, M, Kabesch, M, Liang, L, Dixon, A, Strachan, D, Heath, S, Depner, M, von Berg, A, Bufe, A, Rietschel, E, Heinzmann, A, Simma, B, Frischer, T, Willis-Owen, SA, Wong, K, Illig, T, Vogelberg, C, Weiland, S, von Mutius, E, Abecasis, G, Farrall, M, Gut, I, Lathrop, G, Cookson, W
Médium: Journal article
Jazyk:English
Vydáno: 2007

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