New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1.

New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1.

Although merozoite surface protein 1 (MSP-1) is a leading candidate vaccine antigen for blood-stage malaria, its efficacy in clinical trials has been limited in part by antigenic polymorphism and potentially by the inability of protein-in-adjuvant vaccines to induce strong cellular immunity. Here we...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Goodman, A, Epp, C, Moss, D, Holder, A, Wilson, J, Gao, G, Long, C, Remarque, E, Thomas, A, Ammendola, V, Colloca, S, Dicks, MD, Biswas, S, Seibel, D, van Duivenvoorde, L, Gilbert, S, Hill, A, Draper, S
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2010

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