The -491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEepsilon4 allele and Alzheimer's disease.

Several studies have attempted to confirm the association between the recently reported polymorphism located at position -491 in the transcriptional regulatory region of the Apolipoprotein E (ApoE) gene and Alzheimer's disease (AD). Results have been inconclusive, possibly due to the use of cli...

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Bibliographic Details
Main Authors: Ahmed, A, MacGowan, S, Culpan, D, Jones, R, Wilcock, G
Format: Journal article
Language:English
Published: 1999