Virulence associated gene 8 of Bordetella pertussis enhances contact system activity by inhibiting the regulatory function of complement regulator C1 inhibitor

Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors that play a role in evading the human immune...

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Bibliographic Details
Main Authors: Hovingh, E, De Maat, S, Cloherty, A, Johnson, S, Pinelli, E, Maas, C, Jongerius, I
Format: Journal article
Language:English
Published: Frontiers Media 2018