Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM

Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive lymphocytes attack the myelin sheath of the central nervous system. B lymphocytes in the cerebrospinal fluid (CSF) of patients with MS contribute to inflammation and secrete oligoclonal immunoglobulins1,2. Epstein–Bar...

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Bibliographic Details
Main Authors: Lanz, TV, Brewer, RC, Ho, PP, Moon, J-S, Jude, KM, Fernandez, D, Fernandes, RA, Gomez, AM, Nadj, G-S, Bartley, CM, Schubert, RD, Hawes, IA, Vazquez, SE, Iyer, M, Zuchero, JB, Teegen, B, Dunn, JE, Lock, CB, Kipp, LB, Cotham, VC, Ueberheide, BM, Aftab, BT, Anderson, MS, DeRisi, JL, Wilson, MR, Bashford-Rogers, RJM, Platten, M, Garcia, KC, Steinman, L, Robinson, WH
Format: Journal article
Language:English
Published: Springer Nature 2022