Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis

Melioidosis, an infectious disease caused by the bacterium Burkholderia pseudomallei, is a common cause of sepsis in Southeast Asia. We investigated whether novel TLR1 coding variants are associated with outcome in Thai patients with melioidosis. We performed exonic sequencing on a discovery set of...

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Detalles Bibliográficos
Main Authors: Wright, S, Emond, M, Lovelace-Macon, L, Ducken, D, Kashima, J, Hantrakun, V, Chierakul, W, Teparrukkul, P, Chantratita, N, Limmathurotsakul, D, West, T
Formato: Journal article
Publicado: Springer Nature 2019