Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells.

The influence of the antidiabetic sulphonylurea tolbutamide on K+ channels of mouse pancreatic beta-cells was investigated using different configurations of the patch clamp technique. The dominant channel in resting cells is a K+ channel with a single-channel conductance of 60 pS that is inhibited b...

詳細記述

書誌詳細
主要な著者: Trube, G, Rorsman, P, Ohno-Shosaku, T
フォーマット: Journal article
言語:English
出版事項: Springer-Verlag 1986