Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells.

The influence of the antidiabetic sulphonylurea tolbutamide on K+ channels of mouse pancreatic beta-cells was investigated using different configurations of the patch clamp technique. The dominant channel in resting cells is a K+ channel with a single-channel conductance of 60 pS that is inhibited b...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Trube, G, Rorsman, P, Ohno-Shosaku, T
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Springer-Verlag 1986