Downregulation of the Na(+)-creatine cotransporter in failing human myocardium and in experimental heart failure.
BACKGROUND:The failing myocardium is characterized by depletion of phosphocreatine and of total creatine content. We hypothesized that this is due to loss of creatine transporter protein. METHODS AND RESULTS:Creatine transporter protein was quantified in nonfailing and failing human myocardium (expl...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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