Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.

Previously we have shown that the imino sugar inhibitor of N-linked glycan processing, N-nonyl-deoxynojirimycin (N-nonyl-DNJ), had antiviral activity in the woodchuck model of chronic hepatitis B virus (HBV) infection. In studying the mechanism of action of this compound, it was discovered that imin...

詳細記述

書誌詳細
主要な著者: Mehta, A, Carrouée, S, Conyers, B, Jordan, R, Butters, T, Dwek, R, Block, T
フォーマット: Journal article
言語:English
出版事項: 2001