Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.

Previously we have shown that the imino sugar inhibitor of N-linked glycan processing, N-nonyl-deoxynojirimycin (N-nonyl-DNJ), had antiviral activity in the woodchuck model of chronic hepatitis B virus (HBV) infection. In studying the mechanism of action of this compound, it was discovered that imin...

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書目詳細資料
Main Authors: Mehta, A, Carrouée, S, Conyers, B, Jordan, R, Butters, T, Dwek, R, Block, T
格式: Journal article
語言:English
出版: 2001