Imaging of HIV-1 envelope-induced virological synapse and signaling on synthetic lipid bilayers.

Human immunodeficiency virus type 1 (HIV-1) infection occurs most efficiently via cell to cell transmission(2,10,11). This cell to cell transfer between CD4(+) T cells involves the formation of a virological synapse (VS), which is an F-actin-dependent cell-cell junction formed upon the engagement of...

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Bibliographic Details
Main Authors: Prins, K, Vasiliver-Shamis, G, Cammer, M, Depoil, D, Dustin, M, Hioe, C
Format: Journal article
Language:English
Published: 2012