Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease

Background Clostridium difficile whole genome sequencing has the potential to identify related isolates, even among otherwise indistinguishable strains, but interpretation depends on understanding genomic variation within isolates and individuals. Methods Serial isolates from two scenarios were whol...

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Bibliographic Details
Main Authors: Eyre, D, Walker, A, Freeman, J, Baines, S, Fawley, W, Chilton, C, Griffiths, D, Vaughan, A, Crook, D, Peto, T, Wilcox, M
Format: Journal article
Language:English
Published: Public Library of Science 2013