Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.

It is of pivotal importance for genome stability that repair DNA polymerases (Pols), such as Pols λ and β, which all exhibit considerably reduced fidelity when replicating undamaged DNA, are tightly regulated, because their misregulation could lead to mutagenesis. Recently, we found that the correct...

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Bibliografski detalji
Glavni autori: Markkanen, E, van Loon, B, Ferrari, E, Parsons, J, Dianov, G, Hübscher, U
Format: Journal article
Jezik:English
Izdano: 2012