Smad-dependent alterations of PPT cholinergic neurons as a pathophysiological mechanism of age-related sleep-dependent memory impairments.

In humans, memory impairments are highly prevalent in the aged population, but their functional and structural origins are still unknown. We hypothesized that circadian rhythm alterations may predict spatial memory impairment in aged rats. We demonstrate an association between sleep/wake circadian r...

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Bibliographic Details
Main Authors: George, O, Parducz, A, Dupret, D, Kharouby, M, Le Moal, M, Piazza, P, Mayo, W
Format: Journal article
Language:English
Published: 2006